CALL FOR PAPERS Pathophysiology of Hypertension The loss of sustained Ca signaling underlies suppressed endothelial nitric oxide production in preeclamptic pregnancies: implications for new therapy
نویسندگان
چکیده
Jennifer Krupp, Derek S. Boeldt, Fu-Xian Yi, Mary A. Grummer, Heather A. Bankowski Anaya, Dinesh M. Shah, and Ian M. Bird Perinatal Research Laboratories, Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin; and Division Maternal Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin; and Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Iowa Hospital and Clinics, Iowa City, Iowa
منابع مشابه
The loss of sustained Ca(2+) signaling underlies suppressed endothelial nitric oxide production in preeclamptic pregnancies: implications for new therapy.
Approximately 8% of pregnancies are complicated by preeclampsia (PE), a hypertensive condition characterized by widespread endothelial dysfunction. Reduced nitric oxide (NO) output in PE subjects has been inferred but not directly measured, and there is little understanding of why this occurs. To address this we have used direct imaging of changes in intracellular Ca(2+) concentration ([Ca(2+)]...
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تاریخ انتشار 2013